High-dose chemotherapy in poor-risk germ-cell tumors.
نویسنده
چکیده
Testicular cancer is a highly curable cancer. However, 30% of patients are refractory to standard therapy and will need additional therapy. This article focuses on the use of high-dose chemotherapy in germ-cell tumors. High-dose chemotherapy use is discussed both in the refractory setting and as either first-salvage or first-line therapy. Various criteria for risk assessment are also discussed.
منابع مشابه
High-Dose Chemotherapy in Poor-Risk Germ-Cell Tumors
Testicular cancer has become a model for a curable neoplasm. The results of the treatment of disseminated germ-cell tumors have dramatically improved by utilization of platinum-containing combination chemotherapy regimens. Patients with metastatic disease are allocated to either good-risk or poor-risk groups according to prognostic classifications or models.[1-3] The standard treatment for good...
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CONTEXT The medical treatment of advanced testicular germ cell tumors has changed over the past 30 years, with long-term survival now achieved in the majority of patients. Clinicians need to be familiar with the available treatment regimens for testicular cancer and their associated toxic effects. OBJECTIVE To review the treatments used for advanced testicular germ cell tumors and their assoc...
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عنوان ژورنال:
- The Lancet. Oncology
دوره 8 3 شماره
صفحات -
تاریخ انتشار 2000